Crutchlow fastest during his final morning warm-up as a full-time MotoGP rider, at Portimao.
LCR team-mate Nakagami second ahead of KTM rookie Binder, who was quickest for most of the session.
Bradl walked away from a fast fall at Turn 9.
MotoGP is making its Portimao debut with Mir having wrapped up the 2020 title last weekend in Valencia, but six riders still in with a mathematical chance of second in the standings, currently held by Morbidelli.
Suzuki and Ducati are tied at the top of the constructors’ standings, with Yamaha also in title contention, 13 points back. If Suzuki clinches the title it would be for the first time since 1982, Ducati for the second time along with 2007, and Yamaha for the first time since 2015.
There is also the possibility of a record 10th different race winner of the season this afternoon.
Iker Lecuona is being forced to miss his third event after a positive Covid test and is being replaced at Tech3 by KTM test rider Kallio. Bradl is replacing injured reigning world champion Marc Marquez, who won’t return until 2021.
Official Portimao MotoGP records:
Miguel Oliveira POR KTM1m 38.892s (2020)